PMA

10:30am - 12:10pm East Coast USA Time

Analytical Characterization of BioTherapeutics

Location: 306B

Chair: – BioTools

PMA

10:30am - 10:50am East Coast USA Time

PMA-01.1 - Understanding and protecting dry proteins

Location: 306B

Presenting Author: – UNC-Chapel Hill

Non-Presenting Author: – UNC-CH

PMA

10:50am - 11:10am East Coast USA Time

PMA-01.2 - Structural Differences in mAbs upon Conjugation of Different Payloads (ADCs) Through the Eyes of Multiple Techniques

Location: 306B

Presenting Author: – Macrogenics

Project Lead: – MacroGenics

PMA

11:10am - 11:30am East Coast USA Time

PMA-01.3 - Current State, Challenges, and Future Opportunities in Studying Structural Information for Viral Protein Stability Throughout the Lifecycle

Location: 306B

Presenting Author: – Purdue University

PMA

11:30am - 11:50am East Coast USA Time

PMA-01.4 - Toward determining amyloid fibril structures using experimental constraints from Raman microscopy

Location: 306B

Presenting Author: – University of Vermont

Project Lead: – University of Vermont

PMA

11:50am - 12:10pm East Coast USA Time

PMA-01.5 - Rapid HPTLS Determination of Low Level Surfactants in Protein Formulations

Location: 306B

Presenting Author: – AbbVie

Non-Presenting Author: – Nirrin Technologies, Inc.

Non-presenting author:

PMA

1:30pm - 3:10pm East Coast USA Time

Chirality in Pharma

Location: 306B

Chair: – BioTools

PMA

1:30pm - 1:50pm East Coast USA Time

PMA-02.1 - Application of Vibrational Circular Dichroism (VCD) in Drug Discovery and Development – Structure Elucidation of Chiral Molecules

Location: 306B

Presenting Author: – GSK

PMA

1:50pm - 2:10pm East Coast USA Time

PMA-02.2 - CANCELLED-Fatty Acids and Phospholipids Reverse Supramolecular Chirality of Insulin Fibrils.

Location: 306B

Presenting Author: – Texas A&M University

PMA

2:10pm - 2:30pm East Coast USA Time

PMA-02.3 - Absolute Stereochemistry Determination for Small Molecule Inhibitors of EP300/CREBBP Acetyltransferase by Vibrational Circular Dichroism

Location: 306B

Presenting Author: – National Center for Advancing Translational Sciences, NIH

Non-Presenting Author: – National Center for Advancing Translational Sciences, NIH

Non-Presenting Author: – National Cancer Institute, NIH

Non-Presenting Author: – National Center for Advancing Translational Sciences, NIH

Non-Presenting Author: – National Cancer Institute, NIH

Non-Presenting Author: – National Center for Advancing Translational Sciences, NIH

Non-Presenting Author: – National Cancer Institute, NIH

PMA

2:30pm - 2:50pm East Coast USA Time

PMA-02.4 - Quantum Cascade Laser-Based Rapid Vibrational Circular Dichroism Spectroscopy and Imaging Systems

Location: 306B

Presenting Author: – Colorado School of Mines

Non-Presenting Author: – Colorado School of Mines Phal Group

Non-Presenting Author: – Colorado School of Mines

PMA

2:50pm - 3:10pm East Coast USA Time

PMA-02.5 - Structural characterization of Plant-based Proteins

Location: 306B

Presenting Author: – Ingredion

PMA

3:50pm - 5:30pm East Coast USA Time

Innovations in Vibrational Spectroscopy for Pharmaceutical Development

Location: 306B

Chair: – Bristol Myers Squibb

Co-Chair: – Bristol Myers Squibb

PMA

3:50pm - 4:10pm East Coast USA Time

PMA-03.1 - Domain Size and Homogeneity Analysis Using Chemical Imaging

Location: 306B

Presenting Author: – Bristol Myers Squibb

Non-Presenting Author: – Bristol Myers Squibb

PMA

4:10pm - 4:30pm East Coast USA Time

PMA-03.2 - Studying Monoclonal Antibody Aggregation Under Flow Using Fourier Transform Infrared Spectroscopic Imaging

Location: 306B

Presenting Author: – Imperial College London

Non-Presenting Author: – Imperial College London

Project Lead: – Imperial College London

PMA

4:30pm - 4:50pm East Coast USA Time

PMA-03.3 - Transmission Raman Spectroscopy, Supporting Pharmaceutical Manufacturing to achieve efficiencies and process understanding in continuous drug product manufacturing.

Location: 306B

Presenting Author: – Agilent Technologies

PMA

4:50pm - 5:10pm East Coast USA Time

PMA-03.4 - Diffusion Mapping with Diffractive Optical Elements for Periodically Patterned Photobleaching

Location: 306B

Presenting Author: – Purdue University

Non-Presenting Author: – Purdue University

Project Lead: – Purdue University

PMA

5:10pm - 5:30pm East Coast USA Time

PMA-03.5 - CANCELLED-Recent advances in deep UV Raman and fluorescence instruments for industrial process analysis and cleaning verification

Location: 306B

Presenting Author: – Photon Systems, Inc.

Non-Presenting Author: – Photon Systems, Inc.

Non-Presenting Author: – Photon Systems, Inc

Non-Presenting Author: – Photon Systems

PMA

10:30am - 12:10pm East Coast USA Time

Solving Industrial Problems with Vibrational Spectroscopy

Location: 306B

Chair: – Bristol Myers Squibb

Co-Chair: – Pfizer

PMA

10:30am - 10:50am East Coast USA Time

PMA-04.1 - Spectroscopic Mapping of 3D Printed Microfluidic Devices for High-Throughput Pharmaceutical Formulation Development

Location: 306B

Presenting Author: – University of Birmingham/Bristol Myers Squibb

Non-Presenting Author: – Bristol Myers Squibb

Non-Presenting Author: – University of Birmingham

PMA

10:50am - 11:10am East Coast USA Time

PMA-04.2 - Development of in-situ variable-temperature low- and mid-frequency Raman spectroscopy to elucidate closely related polymorphs

Location: 306B

Presenting Author: – Pfizer Inc.

PMA

11:10am - 11:30am East Coast USA Time

PMA-04.3 - Optimum Solution for a Calibration-Free Method: Understanding the Role of Numerical Solver Parameters on IOT Prediction of Active Ingredients in Pharmaceutical Powder Blends

Location: 306B

Presenting Author: – Duquesne University

Non-Presenting Author: – Genentech, Inc.

Non-Presenting Author: – Duquesne University

PMA

11:30am - 11:50am East Coast USA Time

PMA-04.4 - Developing spectroscopic calibrations in a bench simulator that transfer to manufacturing equipment

Location: 306B

Presenting Author: – Expo Process Analytics

PMA

11:50am - 12:10pm East Coast USA Time

PMA-04.5 - Comparison of Calibration Burden for Partial Least Squares and Iterative Optimization Technology in Process Analytical Technology Applications

Location: 306B

Presenting Author: – Sentronic US Corp

Project Lead: – Sentronic US Corp

Non-Presenting Author: – Sentronic GmbH

PMA

1:30pm - 3:10pm East Coast USA Time

Analysis of biologicals in blood 1

Location: 306B

Chair: – Toronto Metropolitan University

Co-Chair: – Princess Margaret Cancer Centre

PMA

1:30pm - 2:10pm East Coast USA Time

PMA-05.1 - N-Glycoproteomics of patient-derived xenografts for the discovery of novel cancer biomarkers

Location: 306B

Presenting Author: – Princess Margaret Cancer Centre

PMA

2:10pm - 2:30pm East Coast USA Time

PMA-05.2 - Digital Detection of Proteins

Location: 306B

Presenting Author: – Quanterix Corporation

PMA

2:30pm - 2:50pm East Coast USA Time

PMA-05.3 - Ion extraction of hydrogen rearrangements and heavy isotopes reduced the type II error rate of plasma proteomics

Location: 306B

Presenting Author: – Toronto Metropolitan University

Non-Presenting Author: – YYZ PHARMATECH INC

Non-Presenting Author: – Toronto Metropolitan University

PMA

2:50pm - 3:10pm East Coast USA Time

PMA-05.4 - Overcoming Biopharmaceutical Interferents for Quantitation of Host Cell DNA Using an Automated, High-Throughput Methodology

Location: 306B

Presenting Author: – Merck & Co.

PMA

3:50pm - 5:30pm East Coast USA Time

Generative AI and machine learning advancing pharmaceutical development with vibrational spectroscopy

Location: 306B

Chair: – Boehringer Ingelheim Pharmaceuticals

PMA

3:50pm - 4:10pm East Coast USA Time

PMA-06.1 - Spectroscopic Applications for Pharmaceutical Development

Location: 306B

Presenting Author: – Bristol Myers Squibb Co.

Non-Presenting Author: – Bristol Myers Squibb Co.

PMA

4:10pm - 4:30pm East Coast USA Time

PMA-06.2 - Automation of Quantification and Classification of Raman samples through AI

Location: 306B

Presenting Author: – Ocean Optics

Non-Presenting Author: – Ocean Optics

PMA

4:30pm - 4:50pm East Coast USA Time

PMA-06.3 - Hyper-spectra imaging analysis of PLGA microspheres via machine learning enhanced Raman spectroscopy

Location: 306B

Presenting Author: – Boehringer Ingelheim

PMA

4:50pm - 5:10pm East Coast USA Time

PMA-06.4 - CANCELLED-Spectroscopy data-based machine learning predictive modeling in long-acting injectables drug formulation development

Location: 306B

Presenting Author: – Persist AI

Non-Presenting Author: – Persist AI

PMA

5:10pm - 5:30pm East Coast USA Time

PMA-06.5 - Lasers for optical photothermal infrared microscopy for chemical selective imaging in the biomedical context

Location: 306B

Presenting Author: – Leibniz Institute of Photonic Technology

Non-Presenting Author: – Leibniz Institut of Photonic Technology

PMA

10:30am - 12:10pm East Coast USA Time

Frontiers in Drug Sensing and Nanoendoscopic Theragnostic

Location: 306B

Chair: – University of Montreal

PMA

10:30am - 10:50am East Coast USA Time

PMA-07.1 - Advancing Point-of-care Therapeutic Drug Monitoring with Surface-enhanced Raman Spectroscopy

Location: 306B

Presenting Author: – Technical University of Denmark

Non-Presenting Author: – Technical University of Denmark

Project Lead: – Technical University of Denmark

PMA

10:50am - 11:10am East Coast USA Time

PMA-07.2 - Quantitative SERS analysis of drug precursors

Location: 306B

Presenting Author: – National Research Council Canada

PMA

11:10am - 11:30am East Coast USA Time

PMA-07.3 - The integration of electrophysiology and Raman spectroscopy as a novel label-free platform for structural and functional toxicity

Location: 306B

Presenting Author: – Italian Institute of Technology

Non-Presenting Author: – Italian Institute of Technology and University of Pisa

Non-Presenting Author: – Italian Institute of Technology

Project Lead: – Italian Institute of Technology

PMA

11:30am - 11:50am East Coast USA Time

PMA-07.4 - Integrating Vibrational Spectroscopy and Machine Learning for Fentanyl Screening from Human Nails

Location: 306B

Presenting Author: – Texas Tech University

Non-Presenting Author: – Texas Tech University

PMA

11:50am - 12:10pm East Coast USA Time

PMA-07.5 - Surface Enhanced Raman Spectroscopy for Field Forward Forensics of Fentanyl Laced Illicit Pills

Location: 306B

Presenting Author: – U.S. Army DEVCOM Chemical Biological Center

Non-Presenting Author: – U.S. Army DEVCOM Chemical Biological Center

Non-Presenting Author: – Excet, Inc.

Non-Presenting Author: – U.S. Army DEVCOM Chemical Biological Center

Non-Presenting Author: – U.S. Drug Enforcement Administration

Project Lead: – U.S. Army DEVCOM Chemical Biological Center

PMA

1:30pm - 3:10pm East Coast USA Time

Measuring quality in complex raw materials used in biotech and biopharma: spectroscopic methods of analysis

Location: 306B

Chair: – Nanoscale Biophotonics Laboratory, University of Galway

Co-Chair:

PMA

1:30pm - 1:50pm East Coast USA Time

PMA-08.1 - Collaborative Approaches to Achieve Consistency in Complex Raw Materials

Location: 306B

Presenting Author: – Nu-Tek BioSciences

Non-Presenting Author: – Nu-Tek BioSciences

PMA

1:50pm - 2:10pm East Coast USA Time

PMA-08.2 - Heavy Metals in Fertilizer by X-Ray Fluorescence and Atomic Emission Techniques

Location: 306B

Presenting Author: – Tennessee Technological University

Non-Presenting Author: – Tennessee Technological University

PMA

2:10pm - 2:30pm East Coast USA Time

PMA-08.3 - Forensic techniques to identify and mitigate particle sources in pharma industry raw materials, drug substances or cell therapies.

Location: 306B

Presenting Author: – Lonza AG

Non-Presenting Author: – Lonza AG

PMA

2:30pm - 2:50pm East Coast USA Time

PMA-08.4 - Stability testing of cellulose-based excipients using semi-quantitative spectroscopic and non-linear chemometric methods

Location: 306B

Presenting Author: – US Food and Drug Administration

Non-Presenting Author: – US Food and Drug Administration

PMA

2:50pm - 3:10pm East Coast USA Time

PMA-08.5 - Analytical efficacy of conventional Raman spectroscopy compared with shifted excitation Raman difference spectroscopy (SERDS) in the presence of dominant/varying fluorescence

Location: 306B

Presenting Author: – University of British Columbia

Non-Presenting Author: – Professor

PMA

3:50pm - 5:30pm East Coast USA Time

Making Spectroscopy Deployable On-Line Innovations and Trends in BioPharm PAT

Location: 306B

Chair:

PMA

3:50pm - 4:10pm East Coast USA Time

PMA-09.1 - Novel Flow Cell for Raman Measurements

Location: 306B

Presenting Author: – FIAlab Instruments, Inc.

PMA

4:10pm - 4:30pm East Coast USA Time

PMA-09.2 - CANCELLED-Label-Free Electrokinetics-Modulated Surface-Enhanced Raman Spectroscopy (EK-SERS) for Viral Detection Using Micro/Nano-Optoelectrodes (MNOE)

Location: 306B

Presenting Author: – Virginia Tech

Non-Presenting Author: – Virginia Tech

Project Lead: – Oak Ridge National Laboratory

Project Lead: – Professor

Project Lead: – Virginia Tech

PMA

4:30pm - 4:50pm East Coast USA Time

PMA-09.3 - Solving the epitope mapping enigma for drug discovery, drug design and pre-clinical candidate selection: A transformative solution for the biopharma industry

Location: 306B

Presenting Author: – Protein Dynamic Solutions, Inc.

PMA

4:50pm - 5:10pm East Coast USA Time

PMA-09.4 - CANCELLED-Protein recovery and dye removal from wastewater via modified bubble column

Location: 306B

Presenting Author: – Georgia Institute of Technology

Non-Presenting Author: – Georgia Institute of Technology

Non-Presenting Author: – Massachusetts Institute of Technology

Non-Presenting Author: – Georgia Institute of Technology

PMA

5:10pm - 5:30pm East Coast USA Time

PMA-09.5 - Model Transfer between Process Raman Spectrometers

Location: 306B

Presenting Author: – Bruker Coporation

Non-Presenting Author: – Bruker Corp

Non-Presenting Author: – Bruker Corporation

PMA

10:30am - 12:10pm East Coast USA Time

Analysis of biologicals in blood 2

Location: 306B

Co-Chair: – Toronto Metropolitan University

Chair: – North Carolina State University

PMA

10:30am - 11:10am East Coast USA Time

PMA-10.1 - Fundamentals and Applications of IR Matrix-Assisted Laser Desorption Electrospray Ionization for Direct Analysis, Mass Spectrometry Imaging, and High Throughput and Phenotypic Screening

Location: 306B

Presenting Author: – North Carolina State University

PMA

11:10am - 11:30am East Coast USA Time

PMA-10.2 - Applications of Luminex xMAP Technology for Multiplexed Analysis of Blood-Based Biomarkers

Location: 306B

Presenting Author: – Luminex, A Diasorin Company

PMA

11:30am - 11:50am East Coast USA Time

PMA-10.3 - Comparison of enzyme linked immunoassay detection by colorimetric, fluorescent, chemiluminescent and mass spectrometry

Location: 306B

Non-Presenting Author: – Toronto Metropolitan University

Presenting Author: – YYZ PHARMATECH INC

Non-Presenting Author: – Toronto Metropolitan University

PMA

11:50am - 0:10am East Coast USA Time

PMA-10.4 - Plasmonics-Enhanced Lateral-Flow Immunoassay

Location: 306B

Presenting Author: – Duke University

PMA

1:30pm - 3:10pm East Coast USA Time

Real time and offline analysis for bioprocessing 4.0

Location: 306B

Chair:

PMA

1:30pm - 1:50pm East Coast USA Time

PMA-11.1 - Comprehensive Metals Mass Balance in CHO Cell Processes Using an Automated In-line LC-ICP-MS Platform

Location: 306B

Presenting Author: – Clemson University

Non-Presenting Author: – Clemson University

Project Lead: – Clemson University

PMA

1:50pm - 2:10pm East Coast USA Time

PMA-11.2 - Portable Raman Spectrometers, Fluorescence and Lego Blocks

Location: 306B

Presenting Author:

Non-Presenting Author: – Noble, Inc.

Non-Presenting Author:

PMA

2:10pm - 2:30pm East Coast USA Time

PMA-11.3 - LIBS-While-Drilling: A Breakthrough for Real-Time Downhole Analysis

Location: 306B

Presenting Author: – Impossible Sensing

Non-Presenting Author: – Impossible Sensing

Non-Presenting Author: – Washington University in St. Louis

Non-Presenting Author: – Honeybee Robotics

PMA

2:50pm - 3:10pm East Coast USA Time

PMA-11.5 - Quality by design determined spectroscopic and spectrometric control strategies for drop-on-demand point-of-care pharmaceutical manufacturing

Location: 306B

Presenting Author: – National Institute of Standards and Technology (NIST)

Non-Presenting Author: – National Institute of Standards and Technology (NIST)

PMA